World Map

Melissa's story

Melissa Nelson is a disease intervention specialist with the Jefferson County Department of Health, in Birmingham, Albama, USA. When someone is diagnosed with a sexually transmitted infection, it is Melissa's job to investigate from where it has come and to stop it from spreading further.

"People affectionately call us 'sex detectives'," she says.

When engaging with young people who feel invincible, Melissa asks them, "What would you do if we started to see a drug-resistant strain of gonorrhoea here in Birmingham, Alabama? Because it exists."

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Ashish's story

Dr Ashish Abraham runs medical camps in villages in Madhepura, a rural district in the state of Bihar in northern India, to offer care to the Musahars, part of India's "Scheduled Castes" (i.e. the lowest caste, formerly "the untouchables").

It was during one of these health camps that Ashish found a child with Mycetoma, also known as Madura foot, caused by actinomyces bacteria. It would take several months of antibiotic treatment to fight off the infection.

"We've started building rapport and earning trust," says Dr Abraham. "That is the first step in providing the Musahars with accessible healthcare, including effective treatment of bacterial infections."

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Hilary's story

As an oncologist in the UK, Hilary had treated thousands of patients for cancer over the years, but nothing prepared her for her own cancer diagnosis. "Until you're there, you can't stand in those shoes," she says.

Doctors put Hilary on an aggressive treatment regimen that included chemotherapy and a medication meant to boost the production of white blood cells to strengthen the immune system.

"I was very aware of the risk of sepsis," says Hilary, who completed her treatment successfully 17 years ago. "We need to be having conversations with people across society about the dangers of antimicrobial resistance for cancer patients and others."

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Judith's story

As the head nurse of a neonatal intensive care unit, Judith is always on the look-out for signs of problems, including neonatal sepsis, the body's life-threatening reaction to severe infection. "One moment they seem to be improving and getting better, and in a matter of hours things change," says Judith.

In the case of sepsis, doctors must administer antibiotics quickly. Unfortunately, she and her colleagues have noticed that the standard treatments for neonatal sepsis are increasingly ineffective. Finding good treatment options is becoming harder and harder.

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Helmi's story

Dr Helmi bin Sulaiman had carefully tended to his patient at the University of Malaya, Malaysia. He treated the man for life-threatening bacterial infections in his liver and bloodstream, and then an infection in his lungs. But now the infection had returned.

Dr Helmi was granted special permission known as "compassionate use" to treat the patient with a recently approved antibiotic that is not currently available in Malaysia. After a long recovery, the patient walked out of the hospital infection-free.

"This compassionate use programme has helped us a lot," said Dr Helmi. "But it doesn't solve the problem: I do not have access to the right medications."

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Jemin's story

Just weeks before, the patient was a strong and healthy 25-year-old who farmed and drove a tractor in this region that is known throughout the world for its famous Assam black tea. Now he was unable to walk.

Dr Jemin Webster started running tests and eventually diagnosed the patient with melioidosis, a bacterial infection that is more common in the region than elsewhere.

Jemin administered antibiotics following guidelines, and slowly his young patient began to recover. However Jemin cannot take available antibiotics for granted: "One of the main challenges in treating bacterial infection here is the lack of availability of antibiotics, particularly the narrow-spectrum antibiotics," says Jemin.

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Sergei's story

Together with countries around the world, Ukraine was badly hit by COVID-19. "Many patients were afraid of getting sick and dying, and insisted on getting antibiotics," says Sergei Petrik, a doctor in Mariupol.

Many doctors were scared too. Despite WHO and national guidance not to prescribe antibiotics for COVID-19, Sergei says some pushed ahead, risking antibiotic resistance. Then, as Ukraine was emerging from the pandemic, it was caught in the grip of war.

With injuries mounting and often unsanitary conditions, doctors turned to antibiotics to treat infections. But some of them no longer worked.

"Infection and antibiotic resistance came alongside the war. It's been a hard lesson to use antibiotics wisely," says Sergei.

Gregory's story

Pneumonia. Together with other lower respiratory infections, it is the fourth leading cause of death worldwide.

Gregory Carson, from Perth, knows this threat all too well. In the first half of 2023, he suffered from a bout of pneumonia that made him fear for his life.

"The antibiotic that saved me is 60 years old and cost less than US$5."

His experience motivated him to speak out about the need to develop the next generation of life-saving antibiotics.

"I'm aware of the issue of drug resistance. I wish all inexpensive antibiotics in developed countries had a levy to fund antibiotic resistance research."

Orum's story

When Prudence felt the first contraction, she knew something was wrong. "I was scared. I knew it was not time, but the baby was coming," she recalls. Rushed to the Kawempe Hospital, Prudence gave birth to her son Orum at just 24 weeks.

When doctors discovered Orum had pneumonia, they gave him a first-line antibiotic treatment intravenously. However, Orum did not immediately recover.

It took several rounds of treatment before he was discharged to continue recovery at home. Now Orum is healthy and ready to start school.

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Astrid's story

Astrid was in labour at Geneva University Hospitals when she started to shiver and vomit and her temperature soared to 39.9°C. Doctors realized that she had a life-threatening bloodstream infection, and there wasn't a moment to spare.

"I had worried about my baby, but until then, I had never worried about myself," says Astrid.

Soon, Astrid was being treated with antibiotics intravenously, and she gave birth to a healthy baby girl. "Without antibiotics, I would not be here," she says.

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Chelsea's story

When a drug-resistant infection swept through her COVID-19 ward, Chelsea found herself on the frontline of the COVID-19 pandemic and confronting an outbreak of drug-resistant Klebsiella pneumonia.

"Not only were patients battling with the virus, they then had to face a secondary infection on top of it, which could often not be treated because of antibiotic resistance," says Chelsea.

"It took COVID-19 to make me realise how crucial it is to have effective antibiotics."

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Hassan's story

In southern Syria, expert nurse, Hassan Khatar, is working together with his colleagues to use antibiotics with care. When used wisely, antibiotics have made a huge difference to his patients.

“We must work together with international organisations to increase awareness of how to safely and correctly use antibiotics to prevent antibiotic resistance,” says Hassan, who has worked as a nurse in Syria for the past 30 years.

Hassan suggests that nurses and doctors should attend seminars and learn about new developments in the use of antibiotic treatments and care of patients. “Improving our knowledge and experience will lead towards a better and healthier life for patients.”

All stories

Orum, Melissa, Chelsea, Judith… Every day, people all over the world are grappling with the reality of drug resistance. We must come together to address this crisis and protect our future.

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